Meet Inspiring Speakers and Experts at our 3000+ Global Conference Series Events with over 1000+ Conferences, 1000+ Symposiums
and 1000+ Workshops on Medical, Pharma, Engineering, Science, Technology and Business.

Explore and learn more about Conference Series : World's leading Event Organizer

Back

Meltem Kırlı,

Meltem Kırlı,

University of Agriculture Faisalabad, Pakistan

Title: A heart atlas for breast radiation therapy and the influence of deliniation education on both intra and inter observer variability

Biography

Biography: Meltem Kırlı,

Abstract

Purpose: We developed a heart atlas for breast radiation therapy and evaluated the influence of education on intra and interobserver similarity and cardiac dose reporting.

Materials and Methods: The data of 16 left breast cancer patients were analyzed. Eight observers delineated heart and cardiac subunits [left (LCA) and right (RCA) coronary arteries, left anterior descending artery (LAD), bilateral atrium and ventricles] before the education. A radiologist and radiation oncologist developed the atlas and delineated the gold standard (GS) volumes. Observers repeated the delineation after education. RT plans were made for pre/post-atlas contours. The similarity was assessed by Dice (DSC) and Jaccard (JSC) similarity coefficient indices. The absolute difference rate was calculated for the dose analysis.

Results: The inter-observer similarity increased in heart and all subunits. The intra-observer similarity showed a heterogeneous distribution. The absolute difference rate in dose reporting was statistically significant for the bilateral atrium, right ventricle, LAD, LCA+LAD, RCA’s maximum doses (p<0.05). The maximum dose reporting differences from the GS decreased from 16.9 to 8.9% for LAD (p=0.011); from 14.8 to 9.3% for LCA+LAD (p=0.010).

Conclusion: The cardiac atlas reduces the intra interobserver differences and improves dose reporting consistency. The first intra-observer similarity analysis was made in our study and revealed the need for repeated education to increase consistency.