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Lin Sheng

Yuquan Hosiptal-Tsinghua University, China

Title: Comparison of 3-D ultrasound and magnetic resonance imaging for microwave ablation in the canine splenomegaly model

Biography

Biography: Lin Sheng

Abstract

Microwave ablation is used for the treatment of hypersplenism; image guidance and ablation volume assessment is very important to ensure that the ablation is successful. In this study, 3-D ultrasound (US) and magnetic resonance imaging (MRI) were compared with regard to their accuracy in determining the ablation parameters for microwave ablation in a canine splenomegaly model. Microwave ablation was carried out in the spleen of 13 dogs with congestive splenomegaly. Different combinations of power output and ablation time were used: 60 W for 300 s, 50 W for 360 s and 40 W for 450 s. The volume of the ablation zone was measured by 3-D US and 3-D MRI immediately after microwave ablation, and at one, two and eight weeks thereafter. Compared with 3-D MRI, the ablation zone reconstruction rate was lower with 3-D US (92% vs. 100%). However, there was no significant difference with regard to the ablation volume calculated soon after the ablation and one week and two months later. Therefore, 3-D US may be a useful technique for quantifying the volume of microwave ablation zones in the spleens of experimental animals and may be a promising method for clinical examinations.