Saira Naz Sufian
The Aga Khan University Hospital, Pakistan
Title: Accuracy of M.R.I in pretreatment lymph node assessment in gynecological malignancies
Biography
Biography: Saira Naz Sufian
Abstract
Objective: To determine the accuracy of MRI in detection of metastasis in pelvic and para-aortic lymph nodes from different gynecological malignancies. Place of study: Department of Diagnostic Radiology, Aga Khan University Hospital, Karachi Pakistan. Duration of study: From January 2011 to December 2012. Materials & Methods: It was a retrospective cross sectional analytic study. A sample of 48 women, age range between 20-79 years, fulfilling inclusion criteria were included. All patients had histopathologically proven gynecological malignancies including cervix, endometrium or ovaries and presented for a pretreatment MRI to our radiology department. Results: MRI is 100% sensitive and has 100 % positive predictive value to detect lymph node metastasis in lymph nodes with spiculated margins and it is 100 % sensitive and has 75 % positive predictive value to detect lymph node metastasis in a lymph node with lobulated margins. The sensitivity and positive predictive value of MRI to detect heterogeneous nodal enhancement were 100 % and 75 % respectively. Conclusion: Our study results reinforce that MRI should be used as a modality of choice in the pretreatment assessment of lymph node in proven gynaecological malignancies in order to determine the line of patient’s management, distinguishing surgical from non –surgical cases.